منابع مشابه
A global protein–lipid interactome map
1 Center for Cancer Systems Biology (CCSB), and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA, 2 Department of Genetics, Harvard Medical School, Boston, MA, USA and 3 Proteostasis Therapeutics, Inc., Cambridge, MA, USA * Corresponding author. Proteostasis Therapeutics, Inc., 200 Technology Square, Suite 402, Cambridge, MA 02139, USA. Tel.: þ 1 617 582 9114; Fax: þ ...
متن کاملCharting the NF-κB Pathway Interactome Map
Inflammation is part of a complex physiological response to harmful stimuli and pathogenic stress. The five components of the Nuclear Factor κB (NF-κB) family are prominent mediators of inflammation, acting as key transcriptional regulators of hundreds of genes. Several signaling pathways activated by diverse stimuli converge on NF-κB activation, resulting in a regulatory system characterized b...
متن کاملPSIbase: a database of Protein Structural Interactome map (PSIMAP)
UNLABELLED Protein Structural Interactome map (PSIMAP) is a global interaction map that describes domain-domain and protein-protein interaction information for known Protein Data Bank structures. It calculates the Euclidean distance to determine interactions between possible pairs of structural domains in proteins. PSIbase is a database and file server for protein structural interaction informa...
متن کاملA proteome-scale map of the human interactome network
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ~14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ~30% larger than what is available from small-scale studies published in the literature i...
متن کاملA Proteome-Scale Map of the Human Interactome Network
Just as reference genome sequences revolutionized human genetics, reference maps of interactome networks will be critical to fully understand genotype-phenotype relationships. Here, we describe a systematic map of ?14,000 high-quality human binary protein-protein interactions. At equal quality, this map is ?30% larger than what is available from small-scale studies published in the literature i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Systems Biology
سال: 2010
ISSN: 1744-4292,1744-4292
DOI: 10.1038/msb.2010.100